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Cooperative Learning in the Science Classroom

The effective use of cooperative skills is becoming increasingly necessary to cope successfully in today's team-oriented workplaces. This booklet presents jargon-free cooperative learning skills and strategies suitable for the middle school science student. Strategies suggested capitalize on the interests and strengths of middle school students. Activities suggested involve their interest in how things work, their fascination for new and future technology, and their desire to manipulate materials. Included are suggestions for practicing the working relationship skills that students need. Examples of these skills include staying on task, dealing with distractions, and disagreeing in an agreeable way. (PR)

The effective use of cooperative skills is becoming increasingly necessary to cope successfully in today's team-oriented workplaces.

In Silico Analysis and Modeling of Deleterious Single Nucleotide Polymorphism (SNPs) in Human GATA4 Gene

Research Paper from the year 2016 in the subject Medicine - Human Genetics, , language: English, abstract: Congenital heart disease (CHD) is an abnormality in the structure and function of the heart and great vessels caused by embryonic development disorders, it is highly complex and is not fully understood yet. This study performs a computational analysis of the nsSNPs in the GATA4 gene, to identify the possible mutations and propose a modeled structure for the mutant protein that potentially affects its function. The nsSNPs were analyzed using 5 prediction tools: SIFT, Polyphen-2, I-Mutant 3.0, PhD-SNP and Project Hope. The SNPs on 3’UTR and 5’UTR regions were analyzed using PolymRTS and SNP Function Prediction softwares, respectively. Twenty nine nsSNPs were found to be deleterious and damaging by SIFT and 22 nsSNPs by PolyPhen server; 22 nsSNPs were found to be common in both SIFT and PolyPhen server. Also, 6 nsSNPs were observed to be highly deleterious and damaging as per SIFT and PolyPhen server. Moreover, the PolymiRTS results showed 34 SNPs in the 3’UTR region and only one SNP in 5’ UTR by SNP Function Prediction to be functionally significant. Hence, we hope our results will provide useful information that needed to help researchers to do further study in heart disease in children especially in our country

Research Paper from the year 2016 in the subject Medicine - Human Genetics, , language: English, abstract: Congenital heart disease (CHD) is an abnormality in the structure and function of the heart and great vessels caused by embryonic ...